Day 2 :
José R. Reyes Memorial Medical Center, Philippines
Keynote: The efficacy of bile acids in the treatment of non-alcoholic steatohepatitis: A 10-year systematic review
Time : 09:30-10:15
Higinio T Mappala is a full-time Medical Specialist III and Administrator at the Jose R. Reyes Memorial Medical Center, Manila, Philippines and has served as a University Professor and Dean of two medical schools. He has attended the 3-level training courses on Leadership and Management by the World Gastroenterology Organization held in Florida, USA, Dubrovnic, Croatia and Porto, Portugal. He is a focused Lecturer on NAFLD in local and international conventions.
Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most common forms of chronic liver disease which may progress to Non-Alcoholic Steatohepatitis (NASH). Currently there are no therapeutic strategies for such disease. Only lifestyle modification through diet and exercise were proven to afford some benefit in patients with NAFLD. No pharmacologic agents have so far been approved for the treatment of NAFLD or NASH. Therefore, most clinical efforts have been directed at treating the components of metabolic syndrome, namely obesity, diabetes, hypertension and dyslipidemias. Other interventions are directed at specific pathways potentially involved in the pathogenesis of NAFLD, such as insulin resistance, oxidative stress, pro-inflammatory cytokines, apoptosis, bacterial overgrowth and angiotensin pathway. This lecture aims to show the potential of bile acids as a promising therapeutic option for NAFLD. This is a 10-year systematic review of the effects of bile acids on non-alcoholic fatty liver disease. Bile acids may yet prove to be an effective targeted treatment for non-alcoholic fatty liver disease.
KIST Medical College and Teaching Hospital, Nepal
Keynote: Prevalence of obesity in correlation with physical activity among the school students of Pokhara, Nepal
Time : 10:15- 11:00
Archana Bhaila has completed her BSc in Human Biology from Kathmandu University and her MSc in Physiology from Manipal College of Medical Sciences, Pokhara. She is currently working as a Lecturer in Department of Physiology in KIST Medical College and Teaching Hospital.
Obesity is an emerging major public health problem throughout the world and its prevalence has largely increased over the last decade in both developed and developing countries. Only few studies addressing obesity is available in Nepal. While this global epidemic is well described in the adult population, not much data is available regarding the prevalence of overweight/obesity in children or adolescents amongst developing countries. Therefore the present study was to obtain prevalence of obesity in school children and to analyze the relationship of obesity with physical activity of the students. Anthropometric data was collected from 100 students. Physical activities of the students were assessed with the help of a set of questionnaires. The results of this study showed that the obese/overweight subjects had a greater BMI. Of the total population 3% was obese while 19% was overweight. The prevalence rates of overweight and obesity in girls were higher than in boys. Of our sample, 31% were found to be underweight. Most of the obese/overweight children belonged to the private schools, while majority of the underweight belonged in government school. The association of different types of physical activities (sports, domestic help and motor transportation) with BMI was found to be significant. Thus, we can say that obesity and under nutrition co-exist in Nepalese school-children. This study showed the higher rates of underweight children, even though Nepalese population is starting to have worrisome rates of overweight. There is a great need for information on nutritional status and physical activity in school-age children.