Day 1 :
Keynote Forum
F Buck Willis
Dynasplint System Inc., USA
Keynote: Culmination of Interdisciplinary Protocols for Obesity Reduction
Time : 09:30-10:15
Biography:
F Buck Willis has earned his Medical degree in the British Commonwealth (MBBS) and PhD in Kinesiology. He then directed and completed 12 studies over eight years which led to 20 publications and being chosen as a Fellow of the American College of Sports Medicine. He has over 50 publications (including four books).
Abstract:
Successful obesity reduction must start with identifying and eliminating the causes of this disease. The most common causes which affect an estimated 75% of the US population are hidden food allergies. While these sub-acute allergens do not cause itching, hives, or angioedema, they do cause inflammatory reactions which yield metabolic depression. Other causes include high fructose corn syrup and preservatives like TBHQ (Tertiary Butyl Hydroquinone) which require days to detoxify the volatile, phenol compound. Food allergen elimination itself with ALCAT testing showed significant changes in weight, body fat percentage reduction and BMI reduction (p<0.0001). In that comparison study the second category subjects combined treatment of food allergen elimination with PAN-5 protocols. The combined treatment showed a significantly difference (p<0.0001) with 75% greater weight loss (-12.4 Kg), 80% greater fat percentage reduction (-5.4%) and 70% greater BMI reduction (3.6). The PAN-5 acronym is from the combination of these protocols: Portion-size meal control (consuming <2 cups), five times per day; Aerobic-surge exercise (HR elevated ≥75% max for 2 minutes), performed 5/day; and Natural foods eaten five times per day (within the <2 cup portion size). There is significant evidence that hidden food allergies may be one meaningful cause of the growing obesity epidemic and eliminating food allergens will reduce daily weight gains and empower continual weight loss. The combination of the evidence-based protocols in PAN-5 have shown even greater changes (improvement) by eating smaller portion sizes more frequently, participating in a brief, high intensity aerobic-surge exercise for two minutes (5 days) and eating natural foods five times a day (within the portion size).
Keynote Forum
Hani Oweira
Hirslanden Clinics, Zurich
Keynote: Surgery of the Liver and Intra-operative Interventions. What is possible Today
Time : 10:15- 11:00
Biography:
Hani Oweira is a Surgeon in the Hirslanden Clinics in Zurich and Cham and partner of the Surgical Center of Hirslanden Kliniken Zürich.
Abstract:
Liver resections are performed to manage benign and malignant focal lesions in the liver and the post-operative outcome was improved over time due to improvement of surgical techniques which get benefit from understanding the liver anatomy and segmentation with improvement of hemostasis techniques. Anatomy wise liver is divided to 2 lobes (right and left) ant into 8 segments classified by Couinaud based on vascular inflow and outflow. There are many techniques for liver parenchymal transection started with clamp-crush technique and developed to ultrasonic vibration (harmonic shear), Cavitron Ultrasonic Surgical Aspirator (CUSA), hydrojet, radiofrequency dissector and recently staplers. There are numerous types of resection could be divided to major (>2 segments) and minor (<2 segments) and could be divided into anatomical (right and left hepatectomy, right anterior and posterior sectionectomy and left lateral sectionectomy), non-anatomical resection and individual segmentectomy. There are many other interventional procedures can be done during surgery for hepatic focal lesions rather than surgery as Radiofrequency Ablation (RFA), cryoablation or Irreversible Electroporation (IRE) which usually kept as combined intervention with surgery in deep parenchymal lesions which is difficult to be removed without injuring or scarifying a major hepatic structure. Also one of the elegant techniques in management of hepatic focal lesions especially malignant one is adjuvant or pre-operative angio-embolization or chemo/radio embolization which deprives the lesion from its blood supply and supplying it with chemo or radiotherapy which may decrease the size of lesion and make it easier and accessible to be removed. In addition to that, systemic chemotherapy could have benefit in malignant lesions as it may decrease the size of the lesions and minimize the liver parenchyma needed to be resected to remove the whole lesion and sometimes it changes non-resectable liver lesions to resectable one.
Keynote Forum
Richard Visser
Vera Health Group, Aruba
Keynote: The Aruba Project, a road map for population approach to combating obesity
Time : 11:15-12:00
Biography:
Richard Visser has studied the problem and implemented solutions from many perspectives as a Clinical Researcher, Academic, Educator, Activist, Politician, Entrepreneur, concerned citizen and parent. His work has made vital contributions to a great understanding of the biological, sociological and psychological factors surrounding childhood obesity. He has presented papers in Geneva at the congress hosted by the International Association of the Study of Obesity and he is currently collaborating with the Department of Public and Occupational Health in the Netherlands on a proposal for combating the disease throughout the Caribbean. Early in 2008, he was appointed by the Government of Aruba to Head the Obesity Task Force and a year later, he began his four year term as Aruba’s Minister of Health and Sport.
Abstract:
Obesity as a disease has reached historical, maximal peak values, with nearly one-third of the world’s population suffering from obesity and obesity-related conditions. We are now witnessing the impact of this epidemic upon the global health status, with non-communicable diseases on the rise. We have also witnessed the shortcomings and failures of past actions taken when obesity is already present. In Aruba, a prevalence of 36% of childhood obesity was found in 2005, with a tendency to increase as compared to the data prior to 2000. Actions to improve healthy eating habits, reduce sedentary lifestyle and enable a social environment to prevent obesity were carried out in a systematic plan in the period from 2009-2013 and a positive change was observed in the incidence of obesity compatible with complete deceleration of the epidemic and improvement in health indicators. Through the lessons learned from the project as executed in Aruba, we demonstrated how a specific road map can be developed, implemented and highly successful in addressing the obesity epidemic. The roadmap includes steps such as population AL baseline study, an awareness campaign, an approved action plan by the stakeholders and Government, changes in infrastructure, the creation of an institute to promote a healthy lifestyle, an introduction to the exercise is medicine initiative and a study of progress with ongoing monitoring.
- Obesity and Weight Management | Sports Nutrition| Childhood obesity
Chair
F Buck Willis
Dynasplint System Inc., USA
Co-Chair
Hani Oweira
Hirslanden Clinics, Zurich
Session Introduction
Muhammad Amjad
IGI Insurance Limited, Pakistan
Title: Impact of sports and physical activities on the obesity of school-going children
Biography:
Muhammad Amjad is an experienced General Insurance Professional who has earned over 27 years work experience in three different market in Pakistan, namely Islamabad, Faisalabad and Peshawar. He has completed his MSc in Rural Sociology, MBA Sales and Marketing, Certificate of Insurance CII, UK and PhD in Rural Sociology from University of Agriculture Faisalabad. He has great interest in social and management sciences research particularly child hood obesity, marketing, management, nutrition and general health of people. He is the General Manager and Regional Head at IGI General Insurance Limited; a packages group company, he has served this organization for around 23 years so far. Besides formal education, he has also attended numerous professional courses.
Abstract:
Weight that is higher than the healthy weight for a given height is known as overweight or obese. Body Mass Index (BMI) is considered a screening tool for overweight or obesity. If BMI of a person is less than 18.5 it will be underweight range. If BMI is 18.5 to 25, it will be considered normal. If BMI is 25.0 to 30, it will be within overweight range and If BMI is 30.0 or higher, it will be within obese range. At an individual level, BMI can be used as a screening tool but is not diagnostic of the body fatness or the health of an individual. A trained healthcare provider should perform appropriate health assessments in order to evaluate an individual’s health status and risks. Factors such as food habits, family history, increased BMI, environmental conditions, etc. are responsible for the obesity in children. Issue of children obesity is world spread phenomenon. This study was conducted in two districts in Pakistan with sample size of 600 respondents. Schools were categorized as elite private schools, government schools and rural areas schools. The obtained data then was analyzed by using descriptive statistics, bivariate analysis and multivariate to find the relative significance of independent variables in explaining dependent variable. The obesity of the children was affecting students’ academic performance, physical health and psychological health. A strong inverses relationship was found among sports facilities in schools, physical activities, participation in sport and obesity of the children. All possible measures should be taken by all concerned to address children obesity as this epidemic may make our future assets as sick and sluggish.
Inga Thorsdottir
University of Iceland, Iceland
Title: Feeding in the first year of life and risk for overweight and obesity
Biography:
Inga Thorsdottir is a Professor of Human Nutrition, Faculty of Food Science and Nutrition, School of Health Sciences, University of Iceland. She is currently Dean of the SHS UI. She has coordinated many research projects and supervised doctoral students. She has received many honors for her pioneer and scientific work. She has been involved in nutrition recommendations since the 1990s.
Abstract:
Influences early in life have been observed to program body weight and the risk for developing obesity. Infant feeding has been associated with later BMI measures. High weight gain in infancy has also been associated with later overweight. We investigated infant diet and growth in two nation-wide cohorts (born 1995-96 and 10 years later 2005) through the first year of life and with a follow-up at the age of six years. Recommendations about infant diet were changed in early 2000. The comparison between the cohorts showed lower prevalence of overweight in the latter cohort which could be attributed to a changed diet, e.g. lower protein intake. In a randomized controlled trial comparing infants exclusively breastfed for 4 vs. 6 months, we did not observe a difference in growth between the groups, which was explained by small difference in intake between the two groups. According to several systematic literature reviews there is strong evidence for a protective effect of breastfeeding against overweight and obesity in childhood and adolescence. Furthermore, higher protein intake in infancy and early childhood is convincingly associated with increased growth and higher BMI in childhood. Protein intake between 15 E% and 20 E% in early childhood has been associated with an increased risk of being overweight later in life. Breast-milk is the optimal infant diet and official recommendations world-wide have followed the WHO’s recommendation on exclusive breastfeeding for the infant’s first six months and continued breastfeeding parallel to giving other food until one or two year of age or as long as it suits the family. Increased knowledge has strengthened the evidence for this recommendation but more studies are needed. Beside further studies on infant feeding and later obesity, investigations on early nutrition and e.g. asthma and ADHD are needed.
- Liver Diseases | Liver transplantation and Surgery | Liver and Biliary
Location: 2
Session Introduction
Zhuo Wang
Southern University of Science and Technology, China
Title: Stat3 tyrosine phosphorylation is critical for hepatocellular carcinoma proliferation, survival and angiogenesis in response to lipopolysaccharide
Biography:
Zhuo Wang is a well-qualified, highly skilled and motivated person with more than 8-year work experience in liver disease. She has completed her PhD degree from Hong Kong Polytechnic University in 2014 and currently she is working at Southern University of Science and Technology. Her recent research focuses on liver fibrosis and liver cancer.
Abstract:
Hepatocellular Carcinoma (HCC) is a long-term sequence of chronic inflammatory liver injury and hepatic injury is associated with a defective intestinal barrier and increased hepatic exposure to bacterial products including Lipopolysaccharide (LPS), which promotes hepatocarcinogenesis. Despite its clinical signiï¬cance, mediators responsible for the high risk of inflammation to develop HCC in the chronically injured liver remain to be clarified. Here, we report a novel mechanism by which LPS/Signal Transducer and Activator of Transcription 3 (STAT3) signaling promotes the angiogenesis in HCC both in vitro and in vivo. STAT3 activated by LPS increases the production of Vascular Endothelial Growth Factor (VEGF) by tumor cells, which in turn stimulates the migration and tubulogenesis of endothelial cells through STAT3 activation and hence promotes angiogenesis in HCC. Moreover, our data suggested that hypoxia-induced VEGF expression, which also contributes to angiogenesis in HCC, was in a STAT3-dependent pathway. Our findings not only provide a potential mechanism by which bacterial infection enhances HCC oncogenesis through promoting the angiogenesis in liver, but also suggest that targeting STAT3 might be an effective therapeutic strategy in HCC treatment considering the dual roles of STAT3 in angiogenesis.